Engineering Cell‐Based Systems for Smart Cancer Therapy

نویسندگان

چکیده

Due to the difficulty of targeting systemically delivered therapeutics for cancer, interest has grown in exploiting biological agents enhance tumor accumulation and mediate localized drug delivery. Equipped with onboard sensing active motility, some cells respond specific cues microenvironment, making them ideal candidates smart cancer therapy. Herein, recent progress developments are presented on use four most promising cell-based systems delivery—immune cells, stem platelets, bacteria. Strategies further specificity at tissue cell level discussed, including genetic engineering, chemical surface modification, external physical stimuli. With crucial ongoing efforts addressing safety efficacy living intelligent therapeutics, a new era medicine is horizon.

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ژورنال

عنوان ژورنال: Advanced intelligent systems

سال: 2021

ISSN: ['2640-4567']

DOI: https://doi.org/10.1002/aisy.202100134